β-Endorphin (6-31), human

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

β-Endorphin，一种内源性阿片类神经肽，是一种阿片受体 (opioid receptor) 激动剂。β-Endorphin 优先与 μ-阿片受体结合，在中枢和周围神经系统的某些神经元中产生，是人类产生的三种内啡肽之一。β-Endorphin 可以用于减轻压力和维持体内平衡，参与神经系统疼痛感知的调节。

β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation.

β-Endorphin (0.03 to 1.00?μg/kg, i.p., once) impairs retention of a one-trial inhibitory avoidance task in a dose-dependent manner in male Swiss mice immediately post-training. Also, it works in the process of memory consolidation.Animal Model:Adult male Swiss mice (22-25 g)Dosage:0.03, 0.10, 0.30 or 1.00 μg/kg Administration:i.p., once Result:Significantly impaired retention at the doses of 0.03 and 0.10?μg/kg while not significantly affect retention as compared with the control group at the two higher doses of 0.30 and 1.00?μg/kg , but tended to increase retention as compared with the dose of 0.10?μg/kg.Increased latencies to step-through at the two higher doses of 0.30 and 1.00?μg/kg but no effect at lower doses.

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Others

Other Targets

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77761-27-4

2909.38

C131H218N34O40

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years